![]() ![]() Risk of supraventricular tachyarrhythmia (tachycardia) Age-related degenerative disease (fibrosis).Irreversible causes of sinus node dysfunction Drug side effects (diltiazem, verapamil, beta-blockers, digitalis, amiodarone, klonidine, procainamide).Age-related degenerative disease (development of fibrosis) of sinoatrial node. ![]() Reversible causes of sinus node dysfunction The causes have been discussed in each respective article. Whenever such symptoms are associated with ECG evidence of sinus node dysfunction, the condition is referred to as sick sinus syndrome. Symptomatic patients typically experience fatigue, dizziness, dyspnea, presyncope/syncope or diminished exercise tolerance. The majority of patients will experience symptoms, although some cases are asymptomatic. Hence, sinus node dysfunction may manifest with any of the four abovementioned conditions. Sinoatrial block (delayed or blocked impulse conduction between the sinoatrial node and the atrium).Īll these conditions have been discussed in detail in the previous articles.Sinus arrest & sinus pause (intermittent failures to discharge impulses).Chronotropic incompetence (inability of the sinoatrial node to adequately increase its automaticity during physical activity).Sinus bradycardia (which in its purest form means that the automaticity is simply diminished).The conditions encircled by the term sinus node dysfunction are as follows: Disturbed automaticity and blocked impulses lead to arrhythmias that characterize sinus node dysfunction. Sinus node dysfunction is an umbrella term for conditions that either affect the automaticity of the sinoatrial node or blocks the impulse from reaching the atria. Sinus node dysfunction and sick sinus syndrome ![]()
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